As we age, the amount of mucopolysaccharides in the body decreases, and as a result, water content also decreases.
Let’s keep our bodies hydrated and youthful.
Dry eyes
Skin is in poor condition.
Knees hurt when going up and down stairs.
As we age, the mucopolysaccharides that help the body retain water begin to decline, causing the body to become drying and leading to various health issues.
To stay youthful forever, let’s consume mucopolysaccharides!
What are “mucopolysaccharides”?
Mucopolysaccharides are substances that retain water around cells and are essential for maintaining good health.
Mucopolysaccharides are substances in which components such as chondroitin sulfate (chondroitin) and hyaluronic acid are aggregated in their natural state.
Mucopolysaccharides are also scientifically known as proteoglycans.
Try “BIORCOVEN,” a health supplement containing mucopolysaccharides!
Established in 1987
Three Key Benefits
01 ｜ The absorption rate is extremely high.
It utilizes chondroitin sulfate—a primary component of mucopolysaccharides—in the Type A form, which offers a very high absorption rate.
*Many commercially available mucopolysaccharide health supplements use ingredients derived from fish, such as sharks (specifically Types C and D).
02 ｜ consuming the whole food
ubstances such as chondroitin sulfate and hyaluronic acid can be consumed naturally in their original form—as mucopolysaccharides—and thus are highly effective once absorbed into the body.
These complexes of mucopolysaccharides are called proteoglycans.
03 ｜ High-quality ingredients from New Zealand
The mucopolysaccharides used as raw materials are sourced from the cartilage of high-quality beef cattle raised on natural pastures in New Zealand, a country renowned for its world-class safety standards.
Health Foods Containing Mucopolysaccharides
Directions: Take 8 to 16 tablets daily with plenty of water.
Net Weight: 100 g (400 mg × 250 capsules) / bottle
| Nutrition Facts / Per 100 g Calories・・・・・290Kcal Protein・・・・・40.5g Fat・・・・・2.2g Carbohydrate・・・・・35.2g Sodium・・・・・4.57g Mucopolysaccharide protein・・・55.3g Fructooligosaccharides・・・8.1g Collagen Peptides・・・・・3.0g | Ingredients: Beef cartilage extract (New Zealand), fructooligosaccharides, whey powder, glucose, collagen peptides, processed oil product containing Bifidobacterium powder (potato starch, Bifidobacterium powder, processed oil) /Calcium from calcined bone, trehalose, flavoring, flavoring (lecithin), emulsifier, thickener (guar gum), (contains beef, milk ingredients, gelatin, and soybeans) |
Example of product pickup store
Department store
Osteopathic Clinic
Bedrock bath
Hair Salon
Four Key Areas of Medical, Clinical, and Safety Evidence
（1） .Clinical Trial on Changes in Extracellular Fluid (Kudan Clinic)
- Principal Investigator: Dr. Hiroyuki Abe (Kudan Clinic)
- Clinical trial participants: 13 middle-aged and older subjects (aged 56–80; mean age 61.5) who took
- The results showed that extracellular fluid increased by an average of 4.5% over a 9-month period.
Key Data：
- Extracellular water content (extracellular fluid) increased significantly. After 3 months of use, it increased by 200 mL (+1.8%), and after 6 months of use, it increased by a cumulative total of 500 mL (+4.5%). This indicates that the majority of the intracellular water loss associated with aging was restored.
- Intracellular water content remained stable. Intracellular fluid volume remained stable at 22.0 L throughout the study period, confirming that hydration occurred entirely in the extracellular space (joint cavities, dermis, and other areas where water retention is most critical). Furthermore, water distribution returned to the ideal ratio characteristic of a youthful, healthy state (the extracellular fluid-to-intracellular fluid ratio increased significantly by 5.5% after 6 months).
- Improvement in Blood Lipids and Maintenance of Vascular Elasticity: The average total cholesterol level for all subjects decreased from 219.1 mg/dL to 204.7 mg/dL. In the high-risk group (5 subjects) with total cholesterol levels exceeding 220 mg/dL, the average value decreased even more dramatically, from 253.2 mg/dL to 230.4 mg/dL, representing an average reduction of 9.1%.
（2） . In dry environments, the moisture content on the skin’s surface increases
- Clinical Director: Dr. Tatsuya Izumi (Director, Hiroo Dermatology Clinic)
- Study Overview: Fifteen participants took part in a 12-week clinical trial conducted from fall through winter (September through December, the driest season when outdoor humidity drops sharply).
- Test Results: Normally, skin moisture levels drop sharply as environmental humidity rises. However, in subjects who received oral BIORCOVEN for 12 weeks, moisture levels in the skin’s stratum corneum not only did not decrease during the dry winter months but actually increased by 2.7 percentage points (a 2.7-point increase). This provides medical proof that the product is effective in retaining moisture deep within the dermis.
（3） Significantly reduces fine lines and deep wrinkles under the eyes
- Clinical Director: Dr. Tatsuya Izumi (Director, Hiroo Dermatology Clinic)
- Test Results: We accurately measured the fine lines around the participants’ eyes. After 12 weeks of oral administration of BIORCOVEN, the number of fine lines under the eyes decreased significantly from an average of 8.4 to 6.5, representing an average reduction of 2 lines (a 22.6% decrease). This demonstrates that an adequate amount of mucopolysaccharides can effectively promote the production of collagen and elastin in the body, helping to restore skin firmness.
（4）Results of Safety Verification Tests
- Joint Research Institutions: Hiroo Dermatology Clinic, Orthomedico Co., Ltd. (a leading Japanese company in clinical food trials), and Mitsubishi Chemical Medience Co., Ltd.
- Study Details: A 12-week safety study was conducted using an overdose regimen of 15 tablets per day (500 mg per tablet). This study covered dozens of medical parameters, including basic physical measurements (blood pressure, pulse), urinalysis, blood tests, biochemical tests for liver and kidney function, and tests for lipid and blood glucose control.
- Overall Conclusion: During the 12-week clinical trial period, no adverse events (toxic side effects) occurred in the subjects, and no abnormalities were observed in the physiological indicators or clinical records related to safety. This supports the excellent long-term safety profile of BIORCOVEN.
Testimonials from Happy Customers
1.「I’m now able to continue doing the ballroom dancing I love so much」
User: Mr. K.O. (56, Saitama)
Testimonial: My wife and I love ballroom dancing and have won numerous competitions. However, my wife began experiencing pain in her knee joints and was struggling with symptoms such as an inability to bend her knees; she was worried she might no longer be able to dance. On someone’s recommendation, she started taking BIORCOVEN, a mucopolysaccharide supplement. Within a week, the pain had almost completely disappeared, and after one month, her knee joints had fully recovered. I also take BIORCOVEN every day so that I can continue enjoying dancing for as long as possible. I am truly grateful to have discovered BIORCOVEN.
2. I didn’t need rehabilitation after my fracture and was able to return to work within a week.
User: Ms. I.A. (65, Hokkaido )
Personal Experience: I fractured my ankle in a bicycle accident and had to wear a cast. The doctor warned me, “Rehabilitation after the cast is removed will likely be extremely painful.” However, thanks to taking mucopolysaccharides for an extended period, I was already able to move both legs completely
on the very day the cast was removed. The doctor exclaimed in surprise, “You don’t need any physical therapy at all! For most people, it would take at least two weeks—it’s truly remarkable.” In the end, I didn’t undergo any rehabilitation at all, and a week later, I was able to return to my job in the kitchen, where I stand for long hours.
3. Four months later, my blood test results had returned to normal, and my dry eye had improved remarkably.
User: Mr. A.M. (55, Yamaguchi )
Personal Experience: A blood test revealed that my gamma-GTP, cholesterol, and triglyceride levels were all elevated. On a friend’s recommendation, I started taking BIORCOVEN, a mucopolysaccharide supplement, and when I had a follow-up test just four months later, it turned out that all my levels had returned to a safe, normal range. Both my doctor and I were very surprised! Furthermore, the severe pain behind my eyes, dryness, and muscle stiffness that had previously troubled me had completely disappeared before I even realized it, and my eyes now stay moist all day long.
4. My stubbornly elevated γ-GTP levels, which had persisted for 10 years, miraculously returned to normal.
User: Mr.M. S (58 years old, Saitama )
Personal Experience: As a salesperson, I frequently attend business dinners and have many opportunities to drink alcohol. For the past 10 years, every time I had a health checkup, I was told that my liver’s γ-GTP level was too high (80 or above). However, without taking any medication—simply by taking the mucopolysaccharide supplement BIORCOVEN every day—my γ-GTP level miraculously dropped to the normal range of 40 in just one year! The quality of my sleep has also improved significantly, and the neck and shoulder stiffness that had plagued me for years has completely disappeared.
5. Anti-Aging Secrets from a Veteran Hairstylist with 30 Years of Experience
User Name: Ms.N. M (70 years old, Tokyo)
Personal Story: I have 30 years of experience in the beauty and body care industry. I possess in-depth knowledge of the skin. Unfortunately, I was diagnosed with breast cancer and underwent surgery. During treatment, I improved my physical condition through radiation therapy and high doses of BIORCOVEN mucopolysaccharides. Not only did I recover very quickly after surgery, but my clients and doctors were also amazed, saying, “Your skin is always supple and radiant, and your overall condition is wonderful!” To age beautifully even 10 years from now, mucopolysaccharides are an absolutely essential part of my daily routine.
6. The postoperative wound healed surprisingly quickly, and its self-healing ability even surprised the attending physician.
User’s name: Ms. N. K. (70 years old, Kagoshima )
Personal Experience: A 2.5-centimeter tumor was found on my heel, and it was surgically removed. I had heard that mucopolysaccharides significantly shorten the postoperative recovery period and accelerate wound healing, so I actively took high doses after the surgery. As a result, the wound healed very quickly and left almost no scar, which surprised my doctor during my postoperative follow-up visit.
7. My blood vessels are as youthful, plump, and supple as those of a young person!
User Name: Ms. M.Y. (72 years old, Fukuoka )
Personal Experience: After taking BIORCOVEN, a mucopolysaccharide supplement, on a regular basis, I recently underwent a thorough cardiovascular examination at the hospital. The doctor was surprised and said, “Your heart is completely healthy! What’s even more surprising is that the elasticity of your blood vessels is exceptional. They’re round, plump, and supple—just like those of a young person!” As described in medical textbooks, I have personally experienced the powerful effects of mucopolysaccharides in maintaining blood vessel elasticity and preventing atherosclerosis, and I feel immensely satisfied and fortunate.
Magazines and Books in Which It Has Been Published
1. 「The Comprehensive Encyclopedia of Cancer Treatment」 (Futami Shobo)
『ガンを治す大事典』（二見書房）
Edited by: Ryoichi Obizu, Doctor of Science
Media Recommendation: This classic medical text comprehensively explores various modern therapies and alternative medicine, and strongly recommends “mucopolysaccharides” as essential building blocks for human cell repair, maintaining the body’s self-healing abilities, and maintaining vascular flexibility.
2. Heal Through Eating! Functional Foods
『食べて治す！機能性食品』（光文社）
Author: Kōshi Asahigaoka
Recommended Article: This article explores the key to awakening the body’s “natural healing power” and provides a detailed explanation of the important role mucopolysaccharides play in cell repair and water transport.
3. The Supplement Bible
『薬より良く効くサプリメント・バイブル』
Author: Earl Mindell
Media Recommendation: The Chinese edition of this book—a globally renowned and authoritative work in the field of nutrition—was supervised by several Japanese medical experts. The book presents a wealth of empirical evidence demonstrating that natural mucopolysaccharide-protein complexes exhibit exceptional efficacy in preventing aging, delaying joint degeneration, and protecting cell membranes.
4. 21 Functional Foods That Help Manage Diabetes
『医師も病院で使う 糖尿病に効く21の機能性食品』
Author: Kōshi Asahigaoka
Recommendations for the Media: This book explicitly identifies “mucopolysaccharides” as one of 21 outstanding functional substances capable of significantly promoting cellular metabolism, stabilizing physiological indicators, and maintaining microcirculation in the pancreas and blood vessels.
5. Croissant
『クロワッサン』（がんを防ぐ12か条）
Media Recommendation: In this special feature from a prominent Japanese lifestyle magazine for women, the article explores “how to maintain immunity and hydration through daily life and diet” and strongly recommends consuming natural foods rich in mucopolysaccharides every day as a measure against aging.
6. Wakasa Health Magazine
『わかさ』（1995年5月）
Recommendations for the Media: The cover features the eye-catching headline, “Rejuvenate Your Entire Body—From Skin to Bones! The Amazing New Nutrient: ‘Mucopolysaccharide Complex,’” and provides a detailed analysis of groundbreaking medical discoveries regarding joint lubrication, bone strengthening, and ultimate skin hydration.
7〜9. Articles have also been published in other magazines and other publications.
Media Endorsements: In addition to the aforementioned authoritative publications and feature articles, this product’s unique ability to retain cellular moisture and its comprehensive health-promoting effects
have been consistently covered and favorably reported in numerous Japanese health, beauty, and wellness magazines over the years. As a result, it has long been loved and trusted by the Japanese public, particularly middle-aged and older adults.
